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December 2004

Features

Cover Story

Making the Case to Managed Care: The Science of Marketing Biologics

Making a case when biotechs market their products to their most cost-conscious customers — managed care organizations — is far different than what a traditional pharmaceutical company might do with HMO partners. It’s all about the science. Not the cost.
Chuck Appleby
PDF

Business

Partnering: Key to Early-Stage Biotech Survival, But At What Cost?

Young companies’ ideas need proof of principle, and devices need a prototype. Most of all, a biotech must find suitable partners to help with early-stage financing and clinical trials.
Carolyn d’Arville, PhD, MS
PDF

Regulatory

Keeping the Ball In Bounds

Biotechs take notice of the government’s crackdown on, and willingness to exact heavy fines for, promotion of off-label drug use.
John Carroll
PDF

Ethics

The 5 Most Pressing Ethical Issues in Biotech Medicine

Third-party payers, employers, providers, and policy makers face moral dilemmas relative to issues about clinical research, costs, and privacy.
Ed Silverman
PDF

Public Health

Biotech Steps Into the Vaccine Breach

Although vaccine manufacturing is extremely tricky and increasingly costly, biotech companies are plowing ahead on the research front.
Stephen Barlas
PDF

Leading Edge

Shaking the Tree of Life

If we have decoded the human genome, then why continue with the tobacco leaf, the kangaroo, and the dog? Researchers are assembling a “parts list” that will help to define genomics’ role in health and disease.
Jack McCain
PDF

Departments

Openers

It’s Not About the Rebate

Sometimes, it’s not about the rebate.
Michael D. Dalzell
PDF

Editorial

Clinical Trial Redux

David B. Nash, MD, MBA, on the future of patient recruitment for clinical trials.
David B. Nash, MD, MBA
PDF

Drugs & Diagnostics

Road To Developing Regulatory Pathway For Biologic Follow-ons Has Many Turns

Whither a regulatory pathway for biologic follow-ons? Also, FDA approvals and denials, and results of clinical trials.
Bob Carlson
PDF

Discourse

Biotech Cheers 4 More Years, But Familiar Struggles Still Ahead

What the next four years may bring.
John Carroll
PDF

Biotech Business

Report: Biotechs Are Next Challenge Health Plan Sponsors Will Face

Proactive strategies for plan sponsors to control biotech expenditures.
Amanda Brower
PDF

In the Pipeline

Biotech developing 324 new products

New survey finds 324 drugs in development for nearly 150 diseases.
Amanda Brower
PDF