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May 2004

Features

Regulatory

Grappling With the Dilemma of Biologic Follow-ons

Generics — a misnomer in biotechnology — are coming, but the process of developing a regulatory pathway is Byzantine and fraught with uncertainty. Biologic follow-ons have subtleties unforeseen when chemical generics first gained FDA approval. Laws are changing, but not as quickly as the science.
Linda Hull Felcone
PDF

Business

Managing Biologics: 4 Case Studies

If specialty pharmacy is your ace in the hole, why worry? How four MCOs are managing biologic products.
Bob Carlson
PDF

Economics

Explaining the Co$t of Biotech Therapies

Nobody said biopharmaceuticals would be inexpensive. This is attributable to multiple factors and the riskiness of the drug-development process.
Bill Edelman
PDF

Q&A

Defining the Value Proposition of Biotech Therapies

Persuading MCOs and employers to buy into the cost of biotech therapies means defining biologics’ value proposition from a payer’s viewpoint.
Bill Edelman
PDF

Clinical Focus

SWOT Analysis for Molecular Diagnostics: Strengths, Weaknesses, Opportunities, and Threats

Daniel Farkas, PhD, and David Bernard, MD, PhD, discuss strengths, weaknesses, opportunities, and threats associated with molecular diagnostics.
Daniel H. Farkas, PhD, HCLD and David W. Bernard, MD, PhD
PDF

Leading Edge

A Method to the mAbness?

It’s the hottest area of biotech drug development, with more than 100 currently in development. If mAbs make life easier for patients with devastating diseases, demand will skyrocket. Payers want want proof of their value.
Jack McCain
PDF

Departments

Editor’s Memo

‘Generics’: This Fight Is Far From Over

Michael D. Dalzell
PDF

Editorial

You Should Have Been There

David B. Nash, MD, MBA
PDF

Drugs & Diagnostics

Who can fill McClellan’s at FDA? Also, approvals and clinical trials.
Bob Carlson
PDF

Discourse: Stateside

States push new laws allowing stem cell research and therapeutic cloning.
John Carroll
PDF

Biotech Business

IPOs feature companies with products in later stages of development.
Amanda Brower
PDF